Identification of Sox17 as a Transcription Factor That Regulates Oligodendrocyte Development

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Identification of Sox17 as a transcription factor that regulates oligodendrocyte development.

Microarray analysis of oligodendrocyte lineage cells purified by fluorescence-activated cell sorting (FACS) from 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP)-enhanced green fluorescent protein (EGFP) transgenic mice revealed Sox17 (SRY-box containing gene 17) gene expression to be coordinately regulated with that of four myelin genes during postnatal development. In CNP-EGFP-positive (CNP...

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ژورنال

عنوان ژورنال: Journal of Neuroscience

سال: 2006

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.1716-06.2006